Well, there are two ways of looking at it.
Man City is by far easiest team too manage. Kompany is best CB ingame and has 6-7l years of playing in him. Aguero is one of 2-3 best strikers with 10 years of career ahead of him. The rest of team is also very solid and relatively young. Last but not least, City is flooding with money. Propably the only club that can buy CR7/Messi still at their peak.
No other team really comes close.
Barca? Constantly troubled by injuries, lacking backup players.
ManU - solid team but troubled with massive debt.
Chelsea? Heavily aging team in need of fast, major rebuild.
Liverpool? Need serious rebuild.
Real Madrid? Solid 2nd place, but competing with Barca in La Liga is not an easy task.
Bayern? Some injury problems, otherwise solid 3rd place.
Thats purely judging team potential - but you might also want to look at how competetive their respective leagues are. PL is NEVER easy to win , no matter how good your squad is. Serie A and Bundesliga are a tad easier. La Liga - as everyone knows, only 2 teams really matter. This is why French teams are interesting thing to try - the top club often have large stadiums, great facilities, good youth systems, and usually 2-3 fantastic players that you can build around ( from top of my head, Pastore and Sakho in PSG, Lloris and Cissokho in OL, Mandanda in OM) but league itself is not that competetetive.
Hope that helps.