I'm managing Arsenal and normally use a 4-3-3.
At the midfield, i use a DM (Bender/Javi Martinez), DLP[s] (Ramsey/Wilshere) and AP (Ozil/Carzola).
**2 good players for each position**
I often dominate games with that formation, but not when playing away against big teams who use 4-4-1-1/ 4-4-2...
Using an Arsenal save, I had Man City at the Etihad on the last day of the Premier League.
I was still unbeaten at that point, so i had all the pressure to finish without a single loss.
Normally I use a 4-3-3, with the midfield being a DM/BWM(d), DLP(s) & and AP(a). But i still got thrashed...