From my experience, I can say that you start to dominate greatly EPL when you a team that consists of 170+ CA players
and when you manage one of top clubs then it doesn't take longer than few season to get such team :)
Two Strikers version and One Striker Attacking version worked amazing with my Rotherham side in Sky Bet League 1, I finished the 1st placed and had the best goal difference in the league by far :)