Well first off make sure you select your best possible starting 11 . If you are playing at home you can try being not so defensive and play a little more attacking . This is simply because even though they are Big teams they will still look to play a little more defensive or conservative away.
Play on the Counter :
Tick Counter Attack BOX
Pick Counter Strategy
Use Shouts such as : Get Ball Forward , Pass into Space, Pump ball into box, Clear the Ball to Flanks and Get stuck in , Drop Deep could also work
Those shouts suit a more direct style of play. In my opinion its better to play direct when you are a major underdog. Playing a possession game against a much superior opposition does not make sense. You have to be efficient with the small amount of possession you'll get.All of this also suits a big, strong striker who you can hoof the ball to or punt it too. What I like about playing a counter-attack based game is that the chance(s) ( It may be only one ) is usually a very good chance because you usually catch the opposition out of position and off guard.
I hope you also have a variety of personnel who have attributes such as Determination, workrate and teamwork . Determination is great for your players because they will possess the grit to try and get back in the game if you are a goal or two down.