In a word, yes. It depends on how much is spread over monthly payments and how many months. As has been said, it will effect your future transfer budgets. However, signing these players might (should) increase your income through merchandise, TV revenue (big players, big games) and prize money (should go further in competitions and finish higher in the league). As has been said, if your finances get so bad that the Chairman may want to leave (and Ashley is not one for sticking around on FM!) then you could get a takeover. This could be a local businessman \ director on the Board or if you're lucky it could be a tycoon who will pump silly money into the club). Personally, I never use monthly installments (because I try to make all clubs I manage sustainable - I work in Finance, it comes with the territory unfortunately) however they can be used to good effect if used and managed carefully.