Try playing a formation with one true DMC. So 4-1-4-1 or 4-1-3-2 (Lee's Liverpool tactics come in 5 variations which are excellent if you're using the 5x5 Benitez mentality) or 4-2-3-1 (which I think would be my preference for a normal tactic for a good Premiership team).
Remember that away from home you are more likely to be facing a team wanting to score, so playing a little more defensively and on the break will possibly help solve some problems.