I always struggle against City and Liverpool too. They both have equally world class players.
I posted in the other thread (14122sirjur). Its not guaranteed wins but if you put it against your Brentfords, Everton, Leicesters etc, use team shouts, train the players in their specific roles and manage stamina you will blitz sides.
There's a dude on SI forums who used it ad Red Star. Blitzed a league rival 7-0 away, destroyed them. Then went up v Man Utd in Europe away and lost 6-2. As expected in that game, play gung-ho you'll get wrecked.
Its designed for teams that fear your side. They sit more defensive, one up top and try to soak pressure. You will destroy them. City, Liverpool etc ain't scared so they will go at you, 3-6 up front.
Tall strikers, fast WBs, a CB that is class (they will make mistakes due to the formations nature), physical machines at HB and CM.
It's just incredibly fun to play with imo.
Demand More shout at 0-0 and 1-0 up. Berate the second you concede etc. Put the formation in all 3 slots to learn quicker.