On my current save i had Hulk and Vucinec or paloschi either of them played well with him, on same save took united job and have Rooney and either Neymar or trung Rooney top scorer in the league two seasons in a row awesome!
I dont play with 2 strikers but i play Aguero up on his own as Complete striker and 19 league goals in 22 ish games over 8 rating 4 hattrick in the season so far and only in december XD and Rooney just behind but Rooney has been very dissapointing so far for me :S
Cardozo as targetman with pato poaching the knock downs
Amauri works well to somehow gets alot alot of goals
Welliton playing off dzekos pretty effective too
Hulk works best (as far as Im concerned) with robinho/aguero playing with him