In FM definetly Ajax.. They've got some decent players in front of the goal. Although their defense is quite rubbish and with Stekelenburg on goal you have a decent keeper as well..
And to set up the youth Ajax is famous for the many talents they've trained over the past years. and when you look in today Ajax squad there are Emanuelson, Vertonghen, Vermeer, Van der Wiel (and a couple of more) who have all been at Ajax since the start of their careers
EDIT: Dind't see you didn't wanne play Ajax and PSV.. Then I would go for Twente they've got a lot of decent (at least IRL) talents, and when you're a bit lucky you can play champions league as well!