I m using Man City currently and am in my first season. I am enjoying success and am in 3rd position after half a season. Won against Arsenal (4-3 after going 3-0 down), Chelsea(3-0), United(2-1) and lost to Liverpool(1-2). I play a high tempo 4-4-2 and my usual line up is:
Joe Hart
Onouha Sakho Richards Garrido
W.Phillips Palombo Ireland Petrov
Huntelaar Robinho
Subs: Schmiechel, Dunne, Zabaleta, Elano, Johnson, Kompany, Sturridge
Palombo is DMC (rare runs, often thru balls, hold up ball)
Ireland is more attacking (mixed runs, often thru balls, often long shots)
Robinho is shadow-type striker (mixed runs, often thru balls)
Huntelaar is main striker (often runs etc)
Use Zabaleta against stronger teams as Onouha is not very strong and so is W.Phillips.
Try this if u want. Huntelaar and Ireland are my main scorers.