maybe try another subforum for tactic help? are you unhappy with one (or more) of your defensive positions? at lb santon should be plenty good, a little young but very solid. cb taylor and coloccini are far from the worst pairing in the league but if that is your problem maybe try kjaer from wolfsburg for about 3.5m, maybe onuoha from city for about the same, he can also cover at rb. simpson is decent but if he isnt cutting it put anita there and he should excel, he is perfect for the midfield but a great rb as well.
overall you do have the players to do well both defensively and scoring, with ba and cisse especially, like i said, try to get some help for your tactic.