Nah not really, the players have a lot of instructions coded into the tactic (wingers man marketing full-backs, etc).
what I would say is that it that mentality tweaks make a big difference:
Defensive - in tough away games and some home games against far superior opposition Counter - As above, in slightly less tricky away/home games. Balanced - When you're not sure. Positive - When you have a slightly better team at home, or a much better team away Attacking - When you have a much better team at home, or away when your so dominant managers set up crazy defensive
Giveaways that you need to tweak mentality are sub 40% possession after 20 mins or a heap of chances against in a 20 min period.