Ah yes, for me it was only the front 3 of Blackburn Rover (Mauro Formica, Ruben Rochina, Junior Hoilett), they completly humilliate my defence (playing with Man City at the time), all games ended like 4-3, 3-2, 3-3, etc... Usually, the best "tactic" against them is finding out why do they score, most likely they score a lot because of a weakness you have, in my case was that they had speed and flair and good passers behind them, and those thing coupled with my high pressing defending line meant they usually had a lot of space behing my defenders and they had a lot of one-on-ones against my keeper. Took me a while to figure that out, only found out because against bigger teams I would drop deeper, and one time I forgot to do that (either against Liverpool or United), and then it clicked. So, find out how they score their goals (long shots? one-on-ones? You just have **** defenders? Headers?), and then try to find a way to dry them out.