Realistic is nice, but this is ridiculous. Diseases like cancer shouldn't be in a game like this, it makes a mockery out of it. Same with swineflu esp since it might just be a single occurance and will just be a seasonal flu after the first 'pandemic'.
Thought it was weird to have living players in your game who were dead in real life (like the guy for espanyol now), but maybe the other way round is even weirder. When you finally meet Lionel Messi, he in my game you died!