You're playing a very fluid system with three specialists. Generally speaking, the more fluid your system, the fewer specialists (like playmakers and particularly a false nine) you should have in your team. I'd recommend you move to a less fluid system - fluid, or even balanced. I like playing rigid systems because I have have more clearly defined roles, and a more rigid system might work in this sense if you're playing a false nine - and then think about how you want your team to play.
So, a false nine. Drops deep, drags defenders around. Totti is perfect for this, but from what I can see you don't have anyone exploiting that space. If I were you, I'd take one winger (either side) and use him as a winger - support. This'll stretch the play and give your other players more room to work in. On the other side, you can have an IF - Attack to exploit the space left, and if necessary the full-back behind him can be set to attack to exploit the space he leaves too. Finally, you want a midfielder breaking forward into the holes the false nine leaves to provide a goal threat. I'd change Pjanic to a CM - Attack for this reason. You can experiment with other things too; I'd be tempted to put De Rossi as my DLP - Defend and change Strootman to a box to box, giving me two points of attack from deeper in midfield, but try whatever you want.
Finally, give it some time. You don't want to just chop and change constantly. Give it five, six, seven games before you are sure the new tactics aren't working. Also, watch the match on comprehensive and if necessary 2D. It helps with understanding how your players move and are positioned (average positions in the analysis tab is also useful for this).
Good luck!