(1) Not the biggest tester so i wouldn't really know, I'd hope it would work on 22, but it works on this FM for sure.
(2) It really depends, you'd probably need to play more passively depending on the roles,
for example maybe on the lest play the IF on support instead or use a VOL on support.
Next time i do post a tactic ( will update this one ) im gonna do Top ,Midtable and Bottom teams.
I do actually have a very similar tactic that i want to post at some point.