TEAM NEWS
Manchester United boss Sir Alex Ferguson must decide whether to recall Wayne Rooney following the striker's return to action for England.
Despite reports to the contrary, Owen Hargreaves must wait to make his long-awaited return from injury after picking up a calf strain.
West Brom could be without striker Peter Odemwingie, who is struggling to recover from a knee strain.
Midfielder Jerome Thomas is also a doubt with a calf injury.
Manchester United
Doubtful: Giggs (hamstring)
Injured: Hargreaves (calf), Valencia (ankle)
West Brom
Doubtful: Mattock (ankle), Odemwingie (knee)
Injured: Cech (foot), Miller (thigh)
MATCH PREVIEW
West Bromwich Albion head to Manchester bidding for a first win at Old Trafford in 32 years. That match, in December 1978, finished 5-3 to the Albion in one of the most memorable games of the era. The Midlands side would end the season in third place, earning manager Ron Atkinson and star midfielder Bryan Robson lucrative moves to Old Trafford several years later.
The Baggies' class of 2010 are led by another young manager making a name for himself in Roberto Di Matteo, who has taken his Championship promotion-winning side to sixth in the table and level on points with Tottenham and Arsenal. Their last outing on the road ended in a first win at Arsenal since 1983, and they are sure to head to the north west in confident mood.
Manchester United's confidence has taken a knock with a series of underwhelming performances, but they remain unbeaten and will look to a 100% home record for comfort, having beaten Newcastle, West Ham and Liverpool in their three games at Old Trafford.
The spotlight will again fall on striker Wayne Rooney, who caused a stir this week after contradicting his manager Sir Alex Ferguson's explanation that his recent absence from the United line-up was down to an ankle injury. The England striker hasn't scored a Premier League goal from open play since March.
MATCH FACTS
Head-to-head
• The Baggies have never beaten United in the Premier League era.
• Their last win over United in any competition came in the League Cup fourth round in December 2003.
• Manchester United have won 11 and lost none of the last 12 league meetings between the sides.
Manchester United
• If selected, Gary Neville will be making his 600th appearance for Manchester United.
• Nani has set up five goals, the highest number of assists in the Premier League (joint with Didier Drogba).
• They have scored in 14 consecutive league matches at Old Trafford.
• United have only twice before earned fewer points after seven Premier League games (2002/03 and 2004/05).
West Brom
• West Brom have made their best-ever start to a Premier League season after seven matches.
• Their win at Arsenal ended a run of 18 Premier League away matches without a win.
• West Brom have lost 49 Premier League away matches.