You using the latest LFCMarshall update? If so, You would have Raffael and Michel Bastos but lose Lewis Holtby. I suggest playing either a 4-2-3-1 or a 4-3-3 with a line up like this:
4-2-3-1:
Hildebrand
Howedes - Matip - Papadopoulos - Fuchs
Neustadter - Jones
Afellay - Raffael - Draxler
Huntelaar
4-3-3:
Hildebrand
Howedes - Matip - Papadopoulos - Fuchs
Jones
Neustadter - (Buy a DLP)
Afellay - Draxler
Huntelaar
If you play a 4-2-3-1 like I said, Make both CM Ball Winning Midfielders, Neustadter was by far one of my top performers in my Schalke save which unfortunately got corrupted. I support Schalke in real life and let me tell you, On this game, The only teams that should create even a slight problem for you is Bayern and Dortmund. Maybe Leverkusen but they never perform on this game, Not to sure why they're brilliant in real life.
P.S: Schalke are having a terrible season this season, Huntelaar is completely off form and with Holtby missing we're looking very nervous on the ball.