Hi LFCForever - the game models countries' different approaches to football as well. I doubt a high tempo approach (ie the attacking) would work as well in eg Italy or Spain although it should work in eg Germany, Holland, Scandinavia. The level of pressing would also be an issue. Sacchi found this out with his Milan side in real life - high tempo and high pressing knackered his players out after just a couple of seasons. I've personally only tested these tactics at League 2 and below in England. I'd never recommend a 4-4-2 in the modern Italian game - at least not with a flat 4 in midfield. In southern European countries, the control variant would probably be the one I'd focus on tinkering around with if attempting to play these tactics there.
On a more general note, it should be possible using the 9.3 patch to now place the defensive line to the same level as the MCa's mentality (it's currently tied to the MCd's mentality) in attacking variants. I've not tested it extensively yet, but the added pressure does bring dividends at the usual risk of making you a little more vulnerable at the back.